Piriformis Syndrome and Deep Gluteal Syndrome are conditions caused by compression or irritation of the sciatic nerve in the buttock area, leading to pain, numbness, or tingling that can radiate down the leg. These syndromes often mimic sciatica and can significantly impact daily activities and quality of life.
At the Stem Cell & PRP Institute of L.A. in Los Angeles, we offer innovative stem cell and platelet-rich plasma (PRP) therapies designed to reduce inflammation, promote tissue healing, and relieve nerve compression associated with these conditions. Under the expert care of Dr. Padra Nourparvar, a board-certified physician with advanced training in regenerative medicine and musculoskeletal disorders, patients from Beverly Hills, West Hollywood, Santa Monica, and across Los Angeles receive personalized, compassionate care.
I had both stem cells and PRP done. I have been suffering from lower back pain for over 12 weeks and it wasn’t getting better. After trying cortisone shots, physical therapy and chiropractic, I found rescue at Dr. Nourparvar’s. He gives you a thorough examination and the stem cell or PRP treatment suggested is for the most comprehensive approach, pursuing the best health benefit.
I highly recommend this doctor.
Understanding Piriformis and Deep Gluteal Syndrome
- Piriformis Syndrome occurs when the piriformis muscle irritates or compresses the sciatic nerve.
- Deep Gluteal Syndrome refers to compression of the sciatic nerve by other deep muscles or fibrous bands in the gluteal space.
Symptoms include:
- Deep buttock pain
- Radiating pain, numbness, or tingling down the back of the leg
- Difficulty sitting for long periods
- Pain worsened by sitting, climbing stairs, or squatting
These conditions can be caused by muscle spasms, trauma, anatomical variations, or prolonged sitting.
How Stem Cell & PRP Therapy Help Piriformis & Deep Gluteal Syndrome
Traditional treatments like physical therapy and medications focus on symptom management but may not address underlying tissue damage. Regenerative therapies aim to:
- Reduce inflammation around the sciatic nerve and surrounding muscles
- Promote healing of irritated or damaged muscles and soft tissues
- Decrease nerve compression and improve nerve function
- Restore flexibility and strength in the gluteal muscles
Stem cell therapy delivers mesenchymal stem cells to promote repair and modulate inflammation.
PRP therapy provides concentrated growth factors that accelerate healing and reduce pain.


Treatment Options at Stem Cell & PRP Institute of L.A.
Our Los Angeles clinic offers tailored regenerative treatment plans, including:
Targeted PRP Injections
Precise application to inflamed muscles and nerve areas to relieve pain and promote healing.
Stem Cell Therapy
Local or intravenous administration to enhance tissue repair and reduce neuroinflammation.
Physical Therapy Integration
Coordinated rehabilitation to restore muscle function and prevent recurrence.
Personalized Care
Customized treatments based on patient symptoms and lifestyle.
Research Papers: Advancing Evidence-Based Treatment
- Platelet-Rich Plasma for Sciatic Nerve Pain, Journal of Orthopaedic Research
- Stem Cell Therapy in Peripheral Nerve Disorders, Stem Cells Translational Medicine
- Management of Deep Gluteal Syndrome: A Clinical Review, Journal of Sports Medicine
Frequently Asked Questions (FAQ)
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Compression or irritation of the sciatic nerve by the piriformis muscle due to muscle spasms, trauma, or prolonged sitting.
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It involves sciatic nerve compression by other muscles or fibrous tissue deeper in the gluteal region, not just the piriformis.
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Yes. These therapies promote healing, reduce inflammation, and improve nerve function for many patients.
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Patients often experience gradual improvement over weeks, with continued benefits from combined regenerative therapy and rehabilitation.
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Yes. When administered by a board-certified specialist like Dr. Nourparvar, treatments are safe and minimally invasive.

Why Choose Dr. Padra Nourparvar for Piriformis & Deep Gluteal Syndrome Care in Los Angeles?
Patients choose Dr. Nourparvar for his expertise and compassionate approach:
- Board-Certified Specialist: Expertise in family medicine and regenerative musculoskeletal therapies.
- Advanced Regenerative Techniques: Use of cutting-edge stem cell and PRP protocols supported by scientific research.
- Personalized Treatment Plans: Designed to address your specific condition and recovery goals.
- Convenient Location: Serving Beverly Hills, West Hollywood, Santa Monica, and the greater Los Angeles area.
Stem Cell & PRP Institute of L.A.
Premier center for regenerative medicine under the leadership of Dr. Padra Nourparvar, a nationally recognized, double board-certified physician with advanced medical training from UCLA, UC Irvine, NYU, and Mount Sinai, we specialize in cutting-edge stem cell therapies designed to restore function, reduce inflammation, and elevate long-term quality of life.
Dr. Nourparvar has received numerous accolades, including the UCLA Vice Provost Prize for Best Research Article of the Year and the Motif Award for Advancement of Health from The Walt Disney Company. With over a decade of experience treating conditions such as kidney failure, stroke, Parkinson’s disease, and more, he brings a rare combination of technical skill and human compassion to every patient encounter.
Get Lasting Relief from Piriformis & Deep Gluteal Syndrome
If you suffer from persistent buttock or leg pain and want to explore advanced regenerative treatments in Los Angeles, contact the Stem Cell & PRP Institute of L.A. today. Schedule a consultation with Dr. Padra Nourparvar to learn how stem cell and PRP therapy can help you reclaim pain-free movement.