Peyronie’s Disease–characterized by penile plaque, curvature, pain, and erectile dysfunction–affects approximately 3-9% of men, impacting both physical health and quality of life. At the Stem Cell & PRP Institute of L.A., located in Beverly Hills, Dr. Padra Nourparvar, a board‑certified expert in regenerative medicine, offers an integrative, non-surgical treatment approach combining PRP injections, stem cell therapy, and low-intensity shockwave therapy (ESWT) to address pain, plaque, and functional limitations for men throughout Los Angeles, including West Hollywood, Culver City, and Santa Monica.
I cannot express enough gratitude for the incredible care I received from Dr. Padra Nourparvar in addressing my persistent sciatica back pain. After being referred to him for his innovative shockwave treatment, I experienced life-changing results that have left me pain-free and immensely satisfied.
From the moment I stepped into Dr. Nourparvar’s clinic, I was met with a warm and welcoming atmosphere. His knowledgeable and compassionate approach immediately put me at ease. What stood out most was his utilization of the latest technology in shockwave treatment, which proved to be a game-changer in my journey to recovery.
Understanding Peyronie’s Disease & Treatment Goals
Peyronie’s Disease develops as hardened fibrotic plaques within the penile tunica albuginea, leading to curvature, penile shortening, and painful erections. Although surgery remains the definitive corrective option, many men prefer less invasive solutions.
Integrative regenerative therapies aim to reduce plaque, alleviate pain, and improve erectile function by repairing tissue and enhancing vascular support.
Research & Clinical Outcomes
- Meta‑analysis of RCTs (151 ESWT patients) shows significant pain reduction and plaque size improvement, though curvature and erectile function results varied
- A 2023 review across seven trials (475 PD patients) confirms ESWT’s ability to reduce plaques, improve curvature and relieve pain, although sexual function gains were limited
- Long-term, low‑ and high‑energy shockwave studies report up to 51% curvature improvement and 76% pain resolution, with sustained benefits and safety over several years
Integrated Treatment Options
PRP (Platelet-Rich Plasma) & Stem Cell Injections
These biologic therapies–sometimes referred to as “P‑Shot” or “CaverStem PD Protocol”–deliver growth factors and regenerative cells directly into or around penile plaques to reduce inflammation and support tissue remodeling. Often combined with ESWT for enhanced outcomes.
Low‑Intensity Shockwave Therapy (ESWT)
Acoustic energy is focused on the plaque to:
- Reduce pain and plaque size (meta‑analyses show significant short-term changes)
- Modestly improve penile curvature in selected patients (pooled significant curvature benefit: RD ≈ 0.13, p=0.05)
- Offer high patient satisfaction and minimal side effects
Combined therapy provides a multimodal approach to encourage plaque remodeling and maintain penile length.
Frequently Asked Questions (FAQ)
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Men in the stable or active phase of PD with soft to moderate (≤60°) curvature, minimal calcification, and bothersome pain or deformity.
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While ESWT alone may not fully correct curvature, it often softens plaque, reduces pain, and supports overall improvement when used with PRP and stem cells.
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Protocols usually span 4-6 weekly ESWT sessions, with one or two PRP or stem cell injections as part of a tailored plan.
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No anesthesia is required. Most men experience mild tapping sensations. Side effects are minimal–typically temporary redness or slight discomfort.
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Many men see reduced pain within one to two weeks, with curvature and plaque softening evident by 4-8 weeks, and longer-term gains over several months.
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Yes. Our Beverly Hills clinic welcomes men from Santa Monica, Brentwood, Downtown LA, Hollywood Hills, and more.
Why Choose Regenerative Therapy with Dr. Nourparvar?
- Board-certified with advanced training in regenerative and biologic therapies
- Published research and early adoption of ESWT, PRP, and stem cells for PD and ED
- Practical experience with thousands of cases and high patient satisfaction across Los Angeles
- Compassionate, family-friendly care in a Beverly Hills setting near Cedars-Sinai
Stem Cell & PRP Institute of L.A.
Premier center for regenerative medicine under the leadership of Dr. Padra Nourparvar, a nationally recognized, double board-certified physician with advanced medical training from UCLA, UC Irvine, NYU, and Mount Sinai, we specialize in cutting-edge stem cell therapies designed to restore function, reduce inflammation, and elevate long-term quality of life.
Dr. Nourparvar has received numerous accolades, including the UCLA Vice Provost Prize for Best Research Article of the Year and the Motif Award for Advancement of Health from The Walt Disney Company. With over a decade of experience treating conditions such as kidney failure, stroke, Parkinson’s disease, and more, he brings a rare combination of technical skill and human compassion to every patient encounter.
Take the Next Step Toward Relief
If Peyronie’s Disease or associated pain is affecting your quality of life, ask us about combining PRP, stem cell injections, and low-intensity shockwave therapy for a non-surgical path to symptom improvement and tissue healing. Contact us to schedule your consultation.