Prolotherapy: A Natural Way to Relieve Pain and Heal Joints

Chronic pain and joint problems affect millions of people, often limiting mobility, work, and quality of life. While medications and surgeries are common approaches, many patients are looking for non-surgical, natural treatments that address the root cause of pain.

One such treatment is Prolotherapy — a safe, minimally invasive injection therapy that stimulates the body’s own healing process. At the Stem Cell & PRP Institute of L.A., we proudly offer prolotherapy as a standalone treatment or in combination with Platelet-Rich Plasma (PRP) Therapy for even stronger results. Treatments are performed by Dr. Padra Nourparvar, a regenerative medicine expert with over 10 years of experience.

What is Prolotherapy?

Prolotherapy (short for proliferative therapy) is a regenerative injection treatment that helps repair and strengthen weakened ligaments, tendons, and joints.

Here’s how it works:

• A solution, usually made of dextrose (sugar water) and saline, is injected into the injured or painful area.
• This causes a mild, controlled inflammation that activates the body’s natural healing response.
• The body responds by producing new collagen fibers, which strengthen and repair the tissue over time.

Unlike pain medications, which only mask symptoms, prolotherapy aims to restore stability and function to the injured area.

Conditions Treated with Prolotherapy

Prolotherapy can help with many chronic musculoskeletal conditions, including:

• Osteoarthritis (knee, hip, shoulder, hand, ankle)
• Joint instability caused by weak ligaments
• Chronic tendon injuries (tennis elbow, golfer’s elbow, Achilles tendon issues)
• Back and neck pain from ligament laxity or disc-related problems
• Sports injuries that don’t heal with rest or physical therapy
• SI joint (sacroiliac) pain
• Whiplash injuries

Because prolotherapy strengthens soft tissues, it is especially effective for pain caused by loose or unstable joints.

Benefits of Prolotherapy

Patients often choose prolotherapy because it is:

• Non-surgical and minimally invasive
• Natural — it stimulates the body’s own healing
• Long-lasting — it repairs tissue instead of masking pain
• Customizable — it can be combined with PRP or stem cell therapy for more powerful results
• Safe — side effects are typically mild (temporary soreness or swelling)

Over time, prolotherapy can lead to:

• Reduced or eliminated pain
• Stronger and more stable joints
• Increased mobility and flexibility
• Better function in daily activities and sports

The Science Behind Prolotherapy

Prolotherapy has been studied for decades, with a growing body of scientific evidence supporting its effectiveness.

• A systematic review in Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders (2016) found that prolotherapy significantly improved pain, function, and stiffness in patients with knee osteoarthritis (Sit et al., 2016).
• A randomized controlled trial published in Annals of Family Medicine (2013) showed that prolotherapy injections led to clinically meaningful improvements in knee pain, stiffness, and function compared to controls (Rabago et al., 2013).
• A study in Pain Physician Journal (2016) demonstrated significant pain reduction and improved function in patients with chronic low back pain after prolotherapy injections (Kim et al., 2016).

These studies confirm that prolotherapy is not just anecdotal — it has real, measurable benefits for chronic pain and joint health.

Prolotherapy + PRP: A Stronger Healing Combination

At our clinic, we also offer prolotherapy combined with Platelet-Rich Plasma (PRP) Therapy.

PRP is made by taking a small sample of your blood, concentrating the platelets (which are full of healing growth factors), and injecting them into the damaged area. When combined with prolotherapy:

• Prolotherapy triggers the healing process.
• PRP amplifies and accelerates healing, bringing in powerful natural growth factors.
• The combination often leads to faster pain relief and stronger, longer-lasting results.

This integrative approach is especially helpful for:

• Advanced arthritis
• Sports injuries
• Chronic tendon or ligament injuries that haven’t healed with other treatments

Why Choose Stem Cell & PRP Institute of L.A.?

At our Los Angeles clinic, you’ll receive expert care and advanced regenerative treatments tailored to your needs.

• Dr. Padra Nourparvar has over a decade of experience in regenerative medicine and has trained at prestigious institutions including UCLA, UC Irvine, Mount Sinai, and NYU.
• We offer prolotherapy, PRP, and stem cell therapy, giving patients multiple non-surgical options.
• Each treatment plan is customized to target the root cause of pain.
• Our focus is on helping patients avoid unnecessary surgery and long-term medications.

A Natural Path to Healing

If you’ve been struggling with joint pain, arthritis, or injuries that just won’t heal, prolotherapy may be the solution you’ve been looking for. By stimulating the body’s natural repair process, it helps strengthen weak tissues, restore stability, and reduce pain — so you can move with confidence again.

At the Stem Cell & PRP Institute of L.A., we’re here to help you find relief and get back to the activities you love.

Interested in prolotherapy or prolotherapy combined with PRP? Contact our clinic today to schedule a consultation with Dr. Padra Nourparvar. 

📞 Call us today at  (310) 361-5480 to book your appointment or click here to schedule a consultation.