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Highlights

Review & Testimonials/Case Examples

Research

Introduction About the Topic

Current Treatments and Side Effects

How stem cells & Other Treatments Work

Highlights of Our Facility

FAQs

STEM CELL & PRP INJECTION IN LOS ANGELES FOR KNEE ARTHRITIS & TENDON PAIN

Highlights

Safe Non Surgical Option*

Avoid surgery in many cases.

Surgery can be expensive dangerous or debilitating with temporary results & long recovery time.

 Stimulates The Body’s Own Healing Ability*

Helps new cartilage & tendon grow from older cartilage & tendon in a process called regeneration.*

Preventing inflammation.

A Natural Treatment, Not Just Pain Control*

Treat the problem at the source instead of temporary pain control.

Faster Recovery*

No down time.   

Return to work the same day.

Ongoing Research Participation

We enroll our patients in ongoing research protocols and data system for collection & analysis of best outcome results from therapies. We keep records of procedures performed in our outcomes database & in shared and published databases. Patients are always treated with the best protocols & treatments based on the latest research data & informed consent on investigational nature of treatments.  Strict sterile protocols & universal precautions are followed by out office and staff.

The Difference

Treatments at other Clinics :

"Patch up" treatments like, addicting pain medications, Steroid injection, surgery (many side effects including weight gain & increased blood sugar, damage to kidneys, heart, stroke & gastric ulcer from NSAIDs.)

May not know how to use ultrasound during the injections which is very critical in ensuring a safe & accurate injection. May use xray with unnecessary radiation for injections instead of ultrasound.

PRP & Sonic wave (ESWT) not used to enhance the effects of Stem Cells.

May not offer option of different bone stem cell types. (only offer drilling bones or low quality umbilical stem cells.)

May use poorly trained non-physician assistants to evaluate & perform injections.

Not FDA compliant.

Treatments at Our Clinic :

Treating the root cause of the problem by regenerating and repairing the damaged regions. Good safety profile with body products from own body.

Precision ultrasound guided injection to joints without any radiation to ensure safe delivery of stem cells & PRP to the correct location. (Shown to increase positive results by 20-40% vs. without ultrasound)

Other modalities like PRP & Sonic Wave use to focus on the whole joint and treating different parts of it instead of just treating one out of several diseased structures in the joint.

Several types of stem cell including Adipose (fat), bone marrow and umbilical cord derived options available.

Needle Free Air-Jet Pain pre Injections option.

We perform our procedures at a private Room by Medical Office Towers* in Los Angeles, with easy access to many Hospitals, Ranked in the top 10 USA Hospitals.

Our physician is a recipient of the prestigious UCLA Vice Provost Prize, the Motif Award sponsored by Walt Disney, and Altamed PACE Clinical Quality Award. His research published in the ULCA Science Journal had also been awarded the best research article of the year. Participate in conferences & up to date with the latest research.

FDA compliant with strict sterile protocols, research participation and no modification of products.

Research Papers

For years, we have done thorough research, gathered results data of patients, and gotten reviews from patients, all with a single purpose in mind – to give you adequate information that will allow you make the best decision with regards to treatment of your condition.

1. Davatchi F, et al. (2016). Mesenchymal stem cell therapy for knee osteoarthritis: 5 years follow-up of three patients.

Osteoarthritis is a degenerative joint disease characterized by the destruction of joint cartilage. Mesenchymal stem cells (MSCs) are found in low numbers in normal cartilage, mainly in the superficial layer, acting as repairing agents. In OA, MSCs are seen in larger numbers, but act chaotic and are unable to repair the cartilage. The synovial membrane becomes inflamed and interacts with the cartilage. Transplanted MSC have the ability to normalize them, redirecting them to their normal function. In a preliminary study, we showed that MSC could improve knee OA in four patients at 6 months. This report shows their long-term follow-up at 5 years. Link to study >>>>> Here

2. Mesenchymal stem cell injections improve symptoms of knee osteoarthritis.

The purpose of this study was to evaluate the clinical and imaging results of patients who received intra-articular injections of autologous mesenchymal stem cells for the treatment of knee osteoarthritis. The study group comprised 18 patients (6 men and 12 women), among whom the mean age was 54.6 years (range, 41 to 69 years). In each patient the adipose synovium was harvested from the inner side of the infrapatellar fat pad by skin incision extension at the arthroscopic lateral portal site after the patient underwent arthroscopic debridement. After stem cells were isolated, a mean of 1.18 × 10(6) stem cells (range, 0.3 × 10(6) to 2.7 × 10(6) stem cells) were prepared with approximately 3.0 mL of platelet-rich plasma (with a mean of 1.28 × 10(6) platelets per microliter) and injected into the selected knees of patients. Clinical outcome was evaluated with the Western Ontario and McMaster Universities Osteoarthritis Index, the Lysholm score, and the visual analog scale (VAS) for grading knee pain. We also compared magnetic resonance imaging (MRI) data collected both preoperatively and at the final follow-up. The results of the study was encouraging and show that intra-articular injection of infrapatellar fat pad-derived mesenchymal stem cells is effective for reducing pain and improving knee function in patients being treated for knee osteoarthritis. Link to study >>>>> Here

3. Platelet-rich plasma: Intra-articular knee injections produced favorable results on degenerative cartilage lesions

Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors experimented in different fields of medicine in order to test its potential to enhance tissue regeneration. The aim of our study is to explore this novel approach to treat degenerative lesions of articular cartilage of the knee. One hundred consecutive patients, affected by chronic degenerative condition of the knee, were treated with PRP intra-articular injections (115 knees treated). The procedure consisted of 150-ml of venous blood collected and twice centrifugated: 3 PRP units of 5 ml each were used for the injections. Patients were clinically prospectively evaluated before and at the end of the treatment, and at 6 and 12 months follow-up. IKDC, objective and subjective, and EQ VAS were used for clinical evaluation. Statistical analysis was performed to evaluate the significance of sex, age, grade of OA and BMI. A statistically significant improvement of all clinical scores was obtained from the basal evaluation to the end of the therapy and at 6-12 months follow-up (P < 0.0005). The results remained stable from the end of the therapy to 6 months follow up, whereas they became significantly worse at 12 months follow up (P = 0.02), even if still significantly higher respect to the basal level (P < 0.0005). The preliminary results indicate that the treatment with PRP injections is safe and has the potential to reduce pain and improve knee function and quality of live in younger patients with low degree of articular degeneration. Link to study >>>>> Here

4. Extracorporeal shockwave therapy for the treatment of knee osteoarthritis: A retrospective study

This retrospective study investigated the effect and safety of extracorporeal shockwave therapy (ESWT) for treatment of knee osteoarthritis (KOA).In this retrospective study, 105 patients with KOA were included. Of those, 60 patients underwent ESWT, whereas 45 patients received laser therapy. Effect was measured by the Numeric Rating Scale (NRS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). In addition, adverse events (AEs) were also recorded in this study. All outcome measurements were evaluated at the end of weeks 1, 6, and 12.Compared with the laser therapy, ESWT showed greater effect in KOA symptoms relief with regard to NRS, WOMAC total, and its subscores at week 6 (P < .05) and week 12 (P < .01) after treatment. No AE, however, occurred in both groups.The results of this retrospective study found that ESWT may be efficacious and safe for the treatment of patients with KOA. It, however, had an intrinsic limitation as a retrospective study. Prospective study with larger sample size is still needed to warrant the result of this study in the future. Link to study >>>>> Here

Review & Testimonials/Case Examples

 “I’m 73 yo and have torn meniscus and OA. 3 orthos told me I needed knee replacement. Heard about stem cell and had umbilical stem cells injected then my PRP injected a month later. My knee doesn’t hurt nor buckle any more. It does still get ‘tired’ and a little sore but it’s only been about 6 wks since stem cells. … I still have personal trainers but all exercises are done while I’m seated.”

Bobbi S.

“I am receiving treatment for severe osteoarthritis of right ankle.

I have previously consulted two surgeons and was a considered a candidate for ankle fusion with no cartilage left in my ankle. . My mobility problems was getting severe but ankle fusion was terrifying due to permanent lame condition that would result with a “successful” outcome to control pain.

I have been treated with PRP followed 6 weeks later by autologous stem cells from fatty tissue taken from my mid-riff, then PRP again after another 6 weeks.

5 months after the initial treatment I have improved greatly with regard to pain and functioning of my ankle. I used to walk with difficulty, for limited distances and use a cane. Now I only use a cane if I am going for a very long walk or a hike.”

Felix Mahr

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Introduction About the Topic

The joint cartilage allows the joint surface to move slowly, the bones are also protected from friction. This allows absorption of shock up to 20 times the body’s weight. It enhances physical movement, and this is of great importance in athletes.

A major degenerative disorder of knee joint is osteoarthritis. It causes the joint cartilage to deteriorate overtime.

Osteoarthritis may also be caused by knee injury, such as a fracture, damage to the tendon, or tear of the ligament.

When a joint is damaged, it becomes unstable, and this results in a wearing away of the articular cartilage. The bone is then subjected to further damage, in addition to the tendon, ligaments, muscles, and lining of the synovial joint.

Knee-based stem cell therapy is slightly invasive. It is a very effective procedure that can reduce inflammation, and repair all damage that may be caused by arthritis, and equally prevent or delay knee replacement surgery.

ACL Tears

ACL is an acronym for anterior cruciate ligament. The ACL is one of the knees main ligament. It prevents the knee joint from undergoing excessive movements. The anterior cruciate ligament is located beneath the knee cap.

AN ACL tear is in most causes caused by a sport-related injury. It also happens during automobile accidents, injuries sustained while working, during rough play or falls.

ACL tears also happen when landing or pivoting from a jump. The knees give way from under the athlete when the anterior cruciate ligament gets torn.

Knee osteoarthritis

Knee osteoarthritis is a condition that affects the cartilage, the synovium of the knee joint, and the bones.

The cartilage allows easy movement for the joint surface and also cushions the bones.

The synovium acts a lining for the joint. It is a soft tissue and produces what is known as the synovial fluid. The synovial fluid is responsible for the lubrication of the knee joint. It also supplies the cartilage with oxygen and nutrients.

A breakdown of these functions causes loss of protection of the knee joints, resulting in bone damage.

Knee osteoarthritis causes stiffness and pain. Symptoms gets worse with time.

Meniscus injuries

The meniscus is a cartilage that cushions the tibia and the femur. Each knee joint has two menisci.

Damage to the menisci occur during intense physical activities that pressurizes the knee joint, or causes it to rotate. A meniscus tear also occurs when one takes a hard tackle in a soccer game or a sudden pivot while at play in a football field.

A meniscus tear is not just an athlete injury. Even an act as simple as getting up suddenly from a squatting posture can cause a tear in the meniscus. It is on record that no less than 500,000 meniscal tears occur yearly in the United States.

Current Treatment at Other Clinics

Current treatment of knee involves using medications for pain, steroid injection, knee surgery and physical therapy which can temporary alleviate the pain.   These treatments are considered a patch up of the problem without treating the root cause of the problem.  Medications & steroids have many side effects including weight gain & increased blood sugar from steroids, damage to kidneys, heart, stroke & gastric ulcer from NSAIDs.  Surgery can be very debilitating with prolong downtime during recovery requiring at times prolonged bed rest & even residing in nursing home for recovery.  It also entails a lot of risk including risk of infection, bleeding, poor surgical outcome to name a few.  At many times surgery fails to alleviate the pain.  Stem cells however, reduce the inflammation and pain that are typical of these conditions. They also work to regenerate and repair the damaged regions 2. Current research on the effect of stem cells in pain management has shown positive results.

Safe Non Surgical Option

We use a combination of newest cutting edge technology in regenerative medicine to stimulate body’s own repair ability to reverse aging and damage.   We use a careful combination of Stem Cells, PRP and Sonic Waves (ESWT) as part of treatment plan designed by the doctor to treat the body.    These are safe investigational treatments that have shown very promising & safe results in thousands of treatments over the 10-20 years in Europe and USA.   They don’t involve using any medications or drugs.  

What Does ESWT, PRP & Stem Cell Therapy Do?

The researchers believe that the therapy works by:

Releasing cytokines into the body to prevent further damage to cartilage and reduce pain and inflammation.

Preventing inflammation that can make osteoarthritis worse.

Creating healthy new cartilage tissues.

Many patients experience improvements in the treated area and other areas, like in a Mayo Clinic study where patients benefited in both knees after experiencing injections in only one.

Stem cell treatment for knee

The first step involved is a careful assessment of the patient’s medical history and any available studies like MRI and X-rays. After the cause & source of pain is recognized a treatment plan is designed.

Embryological stem cells are then obtained and processed.

After the patient is positioned & the site of location is carefully identified with ultrasound the stem cells are injected into the affected joint under visualization of ultrasound. The patient is discharged after a ten-minute rest.

Patients are advised to rest for at least 48 hours upon reaching the home.

See more information about stem cell here

Platelet rich plasma treatment for knee

Platelets are important in body healing. In PRP, the patient is injected with his or her own platelets to enhance the healing of injured joints, muscles, ligaments and tendons.

To perform a PRP, a sample of your blood is taken and spun in a centrifuge. The platelet fraction is then separated and mixed with a little bit of plasma. This is then injected into the affected tissue. Growth factors are released by the platelets that stimulate the production of reparative cells.

To ensure precision, we use ultrasound imaging to guide the injection process. 

ESWT for knee

During examination, our specialists will locate the point where the pain is most intense, and then apply a water-based medium there. This will enhance the transmission of impulses to that area. A probe will then be placed on that area, and treatment begins.

Very minimal pain or an aching sensation occurs after the treatment. This may last for a few days. After subsequent treatment, you will notice an improvement in symptoms, leading to a reduction in the pain.

Read more about ESWT

Conditions Treated:

  • Knee pain
  • Anterior Cruciate Ligament (ACL) Tear or sprain
  • Knee Osteoarthritis
  • Meniscus Injuries
  • Rheumatoid Arthritis
  • Knee Bursitis
  • Knee Tendonitis
  • Collateral ligament injuries, Medial & Lateral Collateral ligament injuries (MCL, LCL)
  • Posterior Cruciate ligament (PCL) injuries
  • Iliotibial band syndrome

What makes our facility special?

At our Los Angeles facility, we have invented modern approaches to orthopedic care. Our approach to treatment is second to none. The harvesting process does not involve any form of drilling, and the stem cells are purified and tested for quality before injection. We also employ ultrasound to help in the precise placement of high dose stem cells at the required site. These cells will then perform their duty, promoting the formation of new tissues. Please note that this process only occurs if the cells have been injected to the exact site. We are experts in this and has seen positive outcome with our treatments. Our licensed physicians have undergone intense training running into thousands of hours, and so, you can be sure that you are in safe hands.

Needle Free Air-Jet Pain pre Injections

Our doctor is one of the few doctors in USA & Los Angeles offering the new technology of needle free injection.   We have introduced our needle free injector for a more comfortable and painless experience.  There are many advantages in using needle free injectors and it is elected to replace traditional injections in the near future.  They allow injections with very small doses of medicine with significantly faster onset and a lot less pain and discomfort.

Our Office is Located at one of America’s Top Health Venue in Beverly Hills Adjacent. Located in Beverly Hills adjacent fancily we serve customers from Los Angeles, Orange county and Ventura County.  We are premier destination for out of town customers from Nevada, Arizona, San Francisco, San Diego & Oregon.  We are proud to be the premier location for the advancement in medical technology and patient comfort in Southern California.    

We perform our procedures at a private Room by Medical Office Towers* in Los Angeles, with easy access to many Hospitals, Ranked in the top 10 USA Hospitals.  These hospitals are ranked nationally in 11 specialties and has been named to the “Honor Roll” in U.S. News & World Report’s “Best Hospitals 2016-17.”

In 2014-15, these medical centers in the Los Angeles area to win the Consumer Choice Award for:

  • Best Overall Healthcare Quality
  • Best Image
  • Best Doctors
  • Best Nurses

You Are in Good Hands!

Dr. Padra Gad Nourparvar is a recipient of the prestigious UCLA vice provost prize, the Motif Award sponsored by Walt Disney, and Altamed PACE Clinical Quality Award. His research published in the ULCA Science Journal had also been awarded the best research article of the year.

He has special affiliation to Cedar Sinai, White Memorial, CHLA, and other top medical institutions. He is a diplomat of Board of Osteopathic FP & Licensed by the Medical Board of California Physician & Surgeons. He is trained by the NY College of Osteopathic Medicine in osteopathic manipulation. Also, he has trained in several physical medicine & rehab hospitals & research facilities including UCLA, UC Irvine, Mount Sinai,  NYU.

As a plus, he is one of the few and first doctor in USA trained in ultrasound guided joint injection for precision guided accurate injections of all joints, needle free air-jet injector.  Dr. P. Nourparvar has been a pioneer in medical technology and advancements including stem cell. He is passionate about natural treatment with very minimal use of medication while also avoiding unnecessary surgical procedures. He is well versed in the latest and most effective anti-aging treatment using PRP and stem cell.

Frequently Asked Questions

From where do stem cells originate?

Stem cells are present in many tissues and organs. The bone marrow of fat cells are the richest source of stem cells. However, the most convenient region for harvesting is the umbilical cord.

Do you use embryonic stem cells?

The stem cells are harvested from the placenta of mothers delivered through CS. The mothers donate these placentas willingly.

What can stem cell therapy potentially treat?

Stem cell therapy is beneficial to a number of conditions such as osteoarthritis, erectile dysfunction, joint pain, renal disease, neurological disorders, autism, cellular rejuvenation, etc.

When will my results show up?

Stem cell therapy relies on your own regenerative healing to occur. We are all different and so is our healing process. Some patients may begin to see their results within few weeks while others may require some months. The time taken for healing to manifest also depends on the severity of the disease.

How effective is stem cell injections for joint?

A study published in Armen Derian2 Clin Med Insights Arthritis Musculoskelet Disord found that On average, patients experienced an 84.31% decrease in resting pain, a 61.95% decrease in active pain, and a 55.68% increase in functionality score at the final follow-up. Patients also reported a mean 67% total overall improvement at study conclusion. 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024328/

How can stem cells promote healing?

Stem cells are basically building blocks that can develop into any kind of tissues. As such, they are able to replace injured or dead cells, or enhance the healing process in various areas of the body.

What’s the Cost of Stem Cell Injection?

The cost of treatment depends on the procedure performed.  We often offer discounts for returning customers or larger packages of treatment using repeated injections or combining different treatments.  We also offer a price match policy on comparing treatments done by board certified physicians.  We also have interest free payment plan options including care credit for qualifying patients. A limited number of insurance companies and Workers compensation may at times cover some of the expenses.  You may be able to get reimbursed by your insurance for your doctor visits & ultrasound cost. The consultation fee can be deducted from your future procedures, making your consolation free of cost to you.

Book a consultation with our experts to see the type of procedure that is right for you.

Does stem cell therapy have any side effects?

Side effects are very minimal. It may be accompanied by minor irritation or pain at the site of injection. Because we are using your own stem cells, the chances of rejection by your immune system are extremely low.

How long will I take to recover?

Stem cell therapy is minimally intensive. You will return to your daily life within 48 hours.

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Stem Cell & PRP Institute of L.A.| General & Men’s Health, Pain & Aesthetics 

 

Dr. Padra Gad Nourparvar

Board Certified in FM: Adults & Pediatrics

Cedars Sinai Medical Office Towers (New Clinic), 8631 West 3rd Street #545E, Los Angeles, CA.

Cedars Sinai Medical Towers Surgical Suit (Old Clinic), 8635 W 3rd St #880W, Los Angeles, CA 90048

(310) 361-5480

Open Hours

Mon – Thu — 8:30am – 6:00pm
Friday — 8:30am – 4:30pm

 

*Claims are based on ongoing research. Please note that results may vary based on a patient’s medical conditions & age and may require a few months & repeated treatments to obtain. Treatments are considered investigational & these claims have not been verified by the FDA.  No claim for curing or treating of any condition is made.  A consultation with our trained Board Certified physician is scheduled before starting your treatments to confirm the procedure would be appropriate for you. 

Stem Cell

Important Disclosure:

Our clinic is not offering stem cells or stem cell therapy as a cure for any condition, disease, or injury. No statements or implied treatments on this website have been evaluated or approved by the FDA. This website contains no medical advice.  We may use biologics from umbilical cord blood, nanofat and bone marrow aspirate that potentially contain stem cells.   Many of information and treatments maybe investigational and may require participation in a research program.  No results or specific outcomes are guaranteed.  Please use this site as an educational source and consult with a physician about options and treatments.